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ISTH Academy Webinar: Pre-Analytical Issues in the Laboratory
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ISTH Academy Webinar: Pre-Analytical Issues in the Laboratory

10/25/2017
When: Wednesday, October 25, 2017
21:00 UTC/GMT

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Pre-Analytical Issues in the Laboratory

ISTH Core Curriculum 19.3, 19.9 –Neurology

October 25, 2017 21:00 - 22:00 UTC

Speakers:

Emmanuel Favaloro "Pre-analytical issues in laboratory testing for thrombosis and hemostasis related assays"

Andrew "Larry" Frelinger III "Platelet testing and point of care tests"

Moderator: Leonardo Pasalic


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Biographies

Emmanuel J Favaloro

Dr Emmanuel J Favaloro is a Principal Hospital Scientist, and in charge of the Haemostasis laboratories at the Institute of Clinical Pathology and Medical Research (ICPMR), located at Westmead Hospital, and part of NSW Health Pathology.  He has (co-)authored well over 450 papers and has presented at numerous national and international meetings. He is the Editor in Chief of Seminars in Thrombosis & Hemostasis, and a member of the editorial/advisory boards of six other international journals, including JTH and Haemophilia. He is a current or past member of several ISTH SSCs and Working Parties and a past member of several CLSI-guideline working groups. His primary interest is laboratory testing and diagnosis related to bleeding and thrombosis, particularly in developing and evaluating new or improved diagnostics.

Andrew "Larry" Frelinger III

Dr. Andrew L. “Larry” Frelinger III is Assistant Professor of Pediatrics at Harvard Medical School and Associate Director of the Center for Platelet Research Studies and Staff Scientist at Children’s Hospital Boston.  Dr. Frelinger received his Ph.D. from Case Western Reserve University in 1986, and began his work on platelets in the laboratory of Dr. Mark Ginsberg, where he developed antibodies that preferentially react with platelet surface GPIIb-IIIa bound to ligand. He subsequently worked in industry and in 1996 joined Accumetrics where he made key contributions to the development and clinical trial testing of the VerifyNow® System for platelet function testing. Dr. Frelinger returned to academia in 1998 as Associate Director of the Center for Platelet Function Studies and Research Associate Professor of Pediatrics at the University of Massachusetts Medical School where he contributed to the design, execution, and interpretation of pharmacodynamic studies of anti-platelet agents in multi-centered international clinical trials. In 2009 he moved his laboratory to Boston Children’s Hospital and Harvard Medical School and has continued work on variability of response to antiplatelet therapy, evaluation of platelet function as a biomarker of therapeutic efficacy in sickle cell disease, and functional analysis of iPS-derived platelets. Dr. Frelinger is a co-chair of the ISTH SSC Subcommittee on Platelet Physiology and the leader on this SSC committee’s project to standardize flow cytometry for evaluation of platelet defects. He is a Principal Editor for the journal Platelets and an Associate Editor for the 4th edition of the book Platelets

Leonardo Pasalic

Leonardo Pasalic is a haematopathologist and clinical haematologist, currently placed at the Institute for Clinical Pathology and Medical Research, NSW Health Pathology, Westmead Hospital, Sydney, Australia. He received his MD in 2004 from the University of New South Wales (UNSW), Australia. He then completed internal medicine and dual laboratory and clinical haematology training at Westmead Hospital. He received his PhD from the Faculty of Medicine, UNSW, Australia, in 2016, for which he investigated various laboratory assays for characterisation of procoagulant platelets and their role in immunothrombosis. His current clinical focus is on venous thromboembolism and anticoagulants, as well as bleeding disorders. He has continued to pursue his interests in assay development in the field of haemostasis and thrombosis, with particular interest in use of flow cytometry for evaluation of platelet-based biomarkers in clinical diagnostics and translational research.

 

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