Vascular Biology

This Subcommittee is focused on basic and translational research related to vascular biology and related (athero)-thrombotic disorders, through the development of biomarkers that require standardization. These topics are: 1] Shed proteins/receptors; 2] Circulating endothelial progenitor and cells (EPC and CEC ); and 3] cell-derivedmicroparticles (MP) . This SSC incroporates hematologists, laboratory scientists, clinicians and industry scientists, and is a forum of exchanges at the interface with other sub-committees (including Malignancy and Hemostasis, and DIC) and with other Societies (such as ISAC)

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Mandate

• To delineate consensual definition and nomenclature
• To propose new methods of measurement
• To adresse issues of practical importance related to pre-analytic variables
• To establish standardized methodologies
• To develop laboratory calibrants and standards
• To organize collaborative studies to validate these objectives and to delineate the clinical relevance of these biomarkers
• To identify areas of controversy or technological need and discuss methodologic approaches to address questions raised.
• To generate, publish and distribute reports, recommendations and other documents concerning the above.

If you are a member of the Society and would like to know how to participate in the work of this group, please join the group to receive updates on activity or submit an Expression of Interest Form to the Chairman or any of the Co-Chairmen. We would be pleased to learn of your interest.

Projects

• Collaborative SSC project on standardization of MP counting using calibrated bead standards and high sensitivity-Flow Cytometric platforms
  
project began: 2014, projected end: 2014

• Collaborative SSC project on development and distribution of traceable reference materials

Official Communications

• Minutes
• Bibliography
• Publication Guidelines