International Society on Thrombosis and Haemostasis, Inc.
Speakers in the Spotlight

As we count down to the Course, each week we highlight speakers who will participate in the 2014 Second Advanced Training Course.

This week the speaker in the spotlight is:

David Lillicrap, Canada

Dr. Lillicrap is a Professor in the Department of Pathology and Molecular Medicine at Queen’s University, Kingston, Canada. Since 2000, he has been the recipient of a Canada Research Chair in Molecular Hemostasis and is a past Career Investigator of the Heart and Stroke Foundation of Ontario. His research program relates to molecular aspects of the hemostatic system with particular emphasis on novel therapeutic approaches and immunological complications of hemophilia A, and the genetics, biology and pathobiology of von Willebrand Factor.
Full Biography online here.

Dr. Lillicrap will give two presentations at the Second Advanced Training course, including one on Challenges in the Diagnosis and Management of the Hemophilias

Excerpt from the Presentation Abstract Below:

"Hemophilia A and B are the two most common forms of severe inherited bleeding disease with incidence rates of approximately 1 in 5,000 and 1 in 25,000 male births, respectively. Both conditions are transmitted as X-linked recessive traits, with the majority of affected subjects being males. However, due to variations in the pattern of X inactivation, approximately 20% of female carriers of hemophilia can also express a mild bleeding tendency, often manifest as menorrhagia.
The diagnosis of hemophilia is made through a combination of clinical and laboratory features. In approximately 60% of cases there will be a preceding family history of the condition."

Full abstract & list of related resources available at the Second Advanced Training Course. Register Now!

 Selected Related Resources:

  • The hemophilias--from royal genes to gene therapy. Mannucci PM, Tuddenham EG. N Engl J Med. 2001 Jun 7;344(23):1773-9
  • Coagulation factor concentrates: past, present, and future. Key NS, Negrier C. Lancet. 2007 Aug 4;370(9585):439-48.

Previous Speakers in the Spotlight can be found here.