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2015 Annual Minutes
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7/1/2015 at 7:49:52 PM GMT
Posts: 80
2015 Annual Minutes

Chairman: James Douketis


1)      Review of the Session:

  • This 2-hour session began with an Introduction by Jim Douketis, outlining the goals of the Perioperative Working Group, its multidisciplinary make-up and ways for ISTH members to become involved.
  • The first presentation by Pierre Albadalejo outlined the challenges in the perioperative management of patients who are receiving dual antiplatelet therapy. This was followed by a presentation by Jerry Levy, outlining the biological basis for managing anticoagulant-associated bleeding.
  • After a discussion period, the third presentation by Marc Samama identified gaps in knowledge relating to laboratory monitoring and administration of different pro-hemostatic agents in the perioperative period, outlining a call-to-action for the Working Group to lead. The final presentation, by Alex Spyropoulos, reviewed and critiqued recently completed and ongoing randomized trials addressed perioperative anticoagulation.
  • Overall, the session was very well-received, with standing-room only attendance of ~150 people.


2)      Future leadership and activities of (applied for) Subcommittee on Perioperative Thrombosis and Hemostasis:

  • Originally, group was formed with a non-hierarchical structure with Jim Douketis as the de facto chair due to linkage with the SSC.
  • With proposed application to a bona fide Subcommittee of the SSC, there is a need for a more structured organization, with a Chair and Co-chairs.
  • There was unanimous agreement that Marc Samama would be the proposed Subcommittee Chair and other current Working Group members would be Co-chairs.


3)      Guidance and guideline development:

  • There was consensus that the field of perioperative thrombosis and hemostasis was a fertile area for guidance document development, including guidance on the topics presented during the educational session.
  • The new Chair, with the assistance of the Co-Chairs would identify and prioritize potential guidance projects, also identifying more junior ISTH members as co-authors.
  • There was general agreement that development of formal practice guidelines was beyond the scope of this group and, indeed, not a direction (at this this time) that was being pursued by the ISTH.


4)      Research activities:

The Working Group identified 2 broad areas of research involvement:

1)      Facilitating research led by Working Group members or other colleagues by providing input and expertise. For example, members could be called up to serve as Steering Committee members or act in another advisory capacity. In addition, members would serve a conduit to collaborative research networks in their home country.

2)      Developing de novo multi-center clinical trials would be an important goal of this group, building on research networks developed by individual member; there would be the potential for concurrent applications to funding agencies across countries.


5)      Potential future studies:

Yaron Shargall, a thoracic surgeon at McMaster University, Hamilton, Canada discussed a proposed randomized trial assessing VTE prevention after thoracic surgery, with feedback provided. The group encouraged Dr. Shargall to continue this research, where evidence is lacking about best practices, and would provide ongoing feedback and, if needed, participation in the study organization. 

Last edited Tuesday, August 18, 2015
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