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2016 Annual Minutes
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6/8/2016 at 5:09:29 PM GMT
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2016 Annual Minutes

Haemotasis &Malignancy SSC Committee meeting Minutes – Montpellier 2016

Chair: Marc Carrier (present)

Co-Chairs: Guy Meyer (present); Simon Noble (regrets); Alok Khorana (regrets); Cihan Ay (regrets); Nigel Mackman (regrets); Joseph Palumbo (regrets).

1)      Prediction and prevention of cancer-associated thrombosis

a.       Biomarkers for the prediction of VTE in Cancer Patients – A Falanga, Italy

 i.      Review of the evidence on the different biomarkers and the risk of cancer-associated thrombosis (CAT)

ii.      Report of the preliminary results of the second cohort (metastatic cancer patients)  of the Hypercan study

b.      Primary prevention of VTE in cancer patients – G Myer, France

i.      Excellent review of the different primary prevention trial in ambulatory cancer patients receiving chemotherapy.

2)      Clinical debate: Pro and con occult cancer screening in patients with unprovoked VTE – M Carrier & G Le Gal.

a.       Review of the recently published literature on the efficacy of occult cancer screening

b.      ACTION:

i.      Proposal for Guidance statement on occult cancer screening in patients with unprovoked VTE

ii.      Interested SSC members: A Delluc (France)and Ramon Lecumberri (Spain)

1.       M Carrier to follow-up with interested members

2.       Send a Proposal to SSC Chair by fall 2016

3)      Recurrent VTE and cancer-associated thrombosis

a.       NETS in cancer-associated coagulopathy – J Thaler, Austria

i.      Review of the new potential importance of NETS in cancer patients

b.      Risk factors for recurrent CAT- A Delluc, France

i.      Excellent review of the risk of recurrent VTE in CAT patients

4)      Tools for clinical research and updates of SSC initiatives

a.       Statistics for Thrombo-Oncologists

i.      Updates on new statistical (methods) requirements for cancer research (competitive risk, complex risk factors, etc.)

b.      Updates:

i.      Coagulopathy in Prostate Cancer Patients Under Androgen Deprivation

1.       ACTION:

a.       Proposal for a cohort study assessing TEG in cancer patients

                                                                                                                  i.      M Carrier to assess potential resources available at SSC meeting on May 27th

                                                    ii.      SSC registry on incidental PE in cancer patients

1.       M Di Nisio has enrolled 461 patients (total sample 600). Should be done within next year.

2.       ACTION:

a.       Final results to be presented in Berlin 2017

                                                   iii.      Other SSC Projects:

1.       S. Noble

a.       Qualitative analyses of VTE in cancer position statement

2.       J. Palumbo

a.       Pediatrics’ VTE cancer guidelines collaboration with the Pediatric SSC group

3.       C. Ay

a.       Use of D dimer in cancer-associated VTE

4.       ACTION:

a.       Aim to complete on-going projects by SSC 2017

                                                           iv.      New SSC project proposal:

1.       H Rasmussen

a.       Active cancer definition in clinical trials

2.       S Noble

a.       Anticoagulation in patients with cancer undergoing chemotherapy treatment

3.       ACTION:

a.       Identify members willing to participate on the projects

b.      Submit proposal to SSC Chair by fall 2017 

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