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SSC: Plasma Coagulation Inhibitors
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 Plasma Coagulation Inhibitors Subcommittee

This subcommittee is focused on clinical and laboratory issues related to natural inhibitors of coagulation and factors associated with heritable thrombophilia, including but not restricted to Antithrombin, protein C, protein S and activated protein C resistance with or without factor V Leiden.

If you are interested in the subcommittee and want to follow its activity, please click "join group" above to sign up as a member (follower).


  • To address issues of practical importance to the research community in the field.
  • To evaluate existing data, determine issues for which data is missing or deficient, identify areas of controversy or pressing clinical need and discuss methodologic approaches to answer questions raised.
  • To create international collaborations for the purpose of planning and executing projects related to the defined needs in the field.
  • To suggest or organize collaborative studies as a result of these activities.
  • To generate, publish and distribute reports, recommendations and other documents concerning the above.
  • To help standardize laboratory methods, and nomenclature if appropriate.
  • To help develop and calibrate laboratory standards.


The following are the ongoing activities of the Subcommittee.

  • Antithrombin, protein C and protein S mutation databases – ongoing project to update the existing antithrombin, protein C and protein S mutation databases and to create the infrastructure for the indefinite maintenance/update of these databases.
  • Investigation into discrepancies in Protein S activity assay results in order to elucidate the cause of marked differences between PS activity results obtained with different manufacturers kits as reported in several external quality assessment/proficiency testing programmes

If you are a member of the Society and would like to know how to participate in the work of this group, please join the group to receive updates on activity or submit an Expression of Interest Form to the Chairman or any of the Co-Chairmen. We would be pleased to learn of your interest.


Official Communications

Recent Forum Activity
2016 Annual Minutes
Posted by: Richard A. Marlar, Thursday, June 23, 2016
Forum: Annual Minutes
2015 Annual Minutes
Posted by: Lacey Schmeidler, Sunday, June 21, 2015
Forum: Annual Minutes
2014 Annual Minutes
Posted by: Richard A. Marlar, Thursday, June 19, 2014
Forum: Annual Minutes
Seeking participants for genetic risk factors of VTE project!
Posted by: Lacey Schmeidler, Wednesday, February 19, 2014
Forum: General Discussion
2014 Milwakee Agenda
Posted by: Lacey Schmeidler, Wednesday, October 30, 2013
Forum: General Discussion
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Related Group News

ISTH Awards the Robert P. Grant Medal to J. Evan Sadler
Posted in ISTH News, Monday, November 26, 2018

The International Society on Thrombosis and Haemostasis (ISTH) has awarded the Robert P. Grant Medal, the highest honor of the Society, to J. Evan Sadler, ... more »

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Jun Teruya
Zsuzsanna Bereczky
Herm Jan Brinkman
Cecilia Guillermo
Vera Ignjatovic
Eriko Morishita


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