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News & Press: ISTH News

The ISTH Endorses New Clinical Practice Guideline on Care Models for Hemophilia Management

Monday, June 27, 2016   (0 Comments)
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 The guideline on Care Models
for Hemophilia Management
was published in Haemophilia

The International Society on Thrombosis and Haemostasis (ISTH) has endorsed a new evidence-based clinical practice guideline on Care Models for Hemophilia Management developed by the National Hemophilia Foundation in partnership with McMaster University. The NHF-McMaster guideline concludes that the integrated care model be used for people with hemophilia and especially for people with hemophilia with inhibitors or at high risk of inhibitors for optimal care based on the certainty of the available evidence.

A number of national and international guidance documents have supported integrated care as the optimal model of care for people with hemophilia. However, the effects of integrated care on patient-important outcomes had not previously been systematically synthesized or compared to alternative models. The guideline addresses these issues and identifies areas for further research to evaluate the optimal composition of the integrated care delivery model and its impact on specific patient outcomes.

NHF sought the expertise of McMaster University, internationally recognized for its work in this field, to assure that the methods used to develop the guidelines adhered to the principles promoted by National Guideline Clearinghouse and the Institute of Medicine.  The guideline was developed to identify best practices in hemophilia care delivery to optimize outcomes for people living with hemophilia across the United States. 

The guideline has been endorsed by the ISTH, World Federation of Hemophilia, and the American Society of Hematology.

A detailed version of this guideline, as well as supplementary materials have been published in the July 2016, Vol. 22, Supplement 3 issue of the journal Haemophilia, available online at: 

An Executive Summary of the Guideline is available at

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