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JTH Editors Preview September Issue

Monday, August 21, 2017   (0 Comments)
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Journal of Thrombosis and Haemostasis (JTH) Editors Pieter Rietsma and Frits Rosendaal are highlighting three articles in the upcoming September issue. From the editors:

We gladly put the spotlight on three contributions to the September issue of JTH. Platelet production from induced stem cells (iPSCs) is the subject of an ISTH 2017 State of the Art article. The review describes how iPSC technology can help improve the safety and efficacy of platelet transfusions. 

 The PRO-RBDD (Prospective Rare Bleeding Disorders Database) study group contributes an original article that establishes what level of factor XIII is sufficient to prevent spontaneous bleeding episodes in patients with congenital factor XIII deficiency. 

RNA aptamers can be used to inhibit coagulation factor function. Albeit that such aptamers have not reached the market for the treatment of thrombosis or bleeding, their potential remains significant. This is evidenced by an article that describes how a kallikrein-targeting RNA aptamer is capable of inhibiting the intrinsic pathway of coagulation. 

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